Downloads
We’re here to guide and support your treatment journey with IBTROZI. Here are some useful resources you can download and refer to whenever you need.
IBTROZI Brochure
Download this brochure if you or someone you love has been diagnosed with advanced ROS1+ NSCLC and is ready to start treatment with IBTROZI.
Discussion Guide
Download this conversational assessment tool to prepare for office visits and check-ups.
Patient Information for IBTROZI
Advocacy and community support
The cancer journey can sometimes feel isolating, but you aren’t alone. Joining a community of people who understand what you’re going through can help you feel supported, share experiences, and find strength together.
Did you know there's a community of people who are here to support you?
These are just a few of the many communities that provide support for people diagnosed with NSCLC:
Join the ROS1ders community
The ROS1ders is a global group of patients and caregivers of patients with ROS1+ cancer. Their goal is to improve outcomes for all ROS1+ cancers through community, education, and research.
Join the GO2 for Lung Cancer community
GO2 for Lung Cancer provides free, personalized, easy-to-understand information about NSCLC, diagnostic testing, and types of treatments, as well as services to help you advocate for yourself as you navigate your cancer journey.
Join the LUNGevity community
LUNGevity provides information and resources in their Rare Mutations and Fusions Gateway, which includes ROS1, to help patients be more active participants in their healthcare decisions, as well as receive support and connection.
The support groups listed above are independent and not affiliated with Nuvation Bio.
Any information they provide is general in nature and not a substitute for professional medical advice.
Tips for connecting
Start small
If you're not ready to share your story, it's okay to start by listening
Share your experience
Your journey can help others who feel alone
Ask questions
Reach out and ask others to share their experiences for valuable insights
Be open
Support can come from patients like you, as well as caregivers, nurses, doctors, and community leaders
You’re part of a community of people who can share inspiration and support for one another
FAQs
Helpful answers to keep you moving forward with IBTROZI
Glossary
Below you’ll find definitions of words and phrases that you may have seen throughout the website.
Biomarker test: A biomarker test may help find specific genetic changes (also called alterations) or proteins in your cancer cells. Biomarker test results can help your healthcare provider find what may be helping your cancer grow and which treatment choices may be most appropriate for you.
Biopsy: A biopsy is the removal of cells, tissues, or fluid, such as those from a tumor, that are sent to a laboratory for testing. A biopsy is used to help determine a diagnosis and can be used for biomarker testing.
Chemotherapy: Chemotherapy is a type of treatment that works to stop the growth or spread of cancer cells. It also works to destroy tumors and cancer cells.
Clinical study: A clinical study is research that tests how well potential new medical approaches work in people. Clinical studies can test methods to prevent, diagnose, or treat a disease.
Duration of response (DOR): DOR is a term used in clinical studies to define how long a person continues to respond to treatment.
H2 blocker: H2 blockers are a short-term treatment used to limit the production of stomach acid.
Immunotherapy: Immunotherapy is a type of treatment that works with the body’s immune system to fight cancer.
Locally advanced: Locally advanced is a term for cancer that has spread beyond where it started and into nearby lymph nodes or tissue. In ROS1 NSCLC, this means that the cancer has spread beyond the lung but is still confined within the chest region and may have spread into nearby lymph nodes.
Long QT syndrome: Long QT syndrome is a problem with the heart’s electrical system. In people with long QT syndrome, the electrical activity between the Q and T electrical waves lasts longer than normal. This can lead to fast or irregular heart rhythms, which can be fatal for some people.
Metastatic: Metastatic is used to describe cancer that has spread from where it first started to other parts of the body. Cancer cells break off from the primary cancer site and form new tumors in other parts of the body. A metastatic tumor is the same type of cancer as the initial tumor.
Non-small cell lung cancer (NSCLC): NSCLC is a type of lung cancer named for the type of cells that make up the cancer. NSCLC is the most common type of lung cancer.
Overall response rate (ORR): ORR is used to define how many people have partially or completely responded to treatment. Partial response is a decrease in the tumor size, but the cancer hasn’t disappeared entirely. Complete response means that tumors have disappeared, but that does not mean that the cancer is cured. Remaining cancer cells may be too small to detect.
Proton pump inhibitor (PPI): PPIs are a type of medicine used to reduce the amount of acid your stomach produces. Stomach acid helps with digestion and can kill harmful bacteria, but when too much stomach acid is produced, acid reflux or stomach ulcers can occur. PPIs work by blocking an enzyme, called a proton pump, that makes stomach acid.
ROS1 positive (ROS1+): ROS1+ describes cells with a genetically altered protein called ROS1. In normal cells, ROS1 is involved in cell signaling and growth. Cancer cells that have ROS1 changes can grow more quickly, causing cancer to grow and spread. Knowing whether a cancer is ROS1+ can help healthcare providers determine the most effective treatment option.
Tyrosine kinase inhibitor (TKI): A TKI is a targeted treatment that blocks a type of enzyme involved in cell growth called a tyrosine kinase. High levels of tyrosine kinases are found in certain cancers and blocking them with a TKI may help keep cancer cells from growing.
NSCLC=non-small cell lung cancer; ROS1+=ROS proto-oncogene 1–positive.